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Updated: Aug 8, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
Published on: April 3, 2014
Assembling a smallpox biodefense by interrogating 5-substituted pyrimidine nucleoside chemical space
Xuesen Fan1, Xinying Zhang, Longhu Zhou
1Department of Chemistry and Biochemistry, Northern Arizona University, Flagstaff, AZ 86011, USA.
Abstract:
The nucleoside 5-formyl-2'-deoxyuridine has been used as a starting point for the generation of novel 5-substituted pyrimidine nucleosides that are shown to possess significant antiviral activity against two representative orthopoxviruses, namely vaccinia virus and cowpox virus.
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