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Dose response to vaginal administration of 1,25-dihydroxyvitamin D3 to cows

N Okura1, N Yamagishi, Y Naito

  • 1Central Veterinary Clinical Center, Kamikawa Chuo Agricultural Mutual Aid Association, Asahikawa, Hokkaido 078-8208, Japan. n-ohkura@mvg.biglobe.ne.jp

Veterinary Journal (London, England : 1997)
|June 9, 2006
PubMed

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The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it produces...
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