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Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
Cardiac metastasis from uterine leiomyosarcoma
F Moreno Antón1, A Casado Herraez, J Puente Vázquez
1Servicio de Oncología Médica, Hospital Clínico San Carlos, Madrid, Spain. laventi2002@yahoo.es
Insights
Cardiac metastases, rare from uterine leiomyosarcoma, can present years after treatment. Early suspicion and surgical intervention may lead to prolonged survival in these exceptional cases.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac metastases are more common than primary heart tumors.
- Carcinomas are more frequent causes of cardiac metastasis than sarcomas.
Observation:
- A rare case of uterine leiomyosarcoma metastasizing to the heart is presented.
- Metastasis occurred 6 years after the initial tumor resection.
Findings:
- The patient underwent surgical resection for the cardiac metastasis.
- The patient survived for 30 months post-surgery without cardiac recurrence.
Implications:
- Cardiac metastasis from uterine leiomyosarcoma, though exceptional, warrants clinical suspicion.
- Surgical treatment for cardiac metastasis can be associated with significant long-term survival.
Abstract:
Cardiac metastases are more frequent than primary heart neoplasias. Nearly any malignant tumour may metastasize to the heart, but the most common are carcinomas rather than sarcomas. We report the case of a patient who presented with heart metastasis 6 years after resection of an uterine leiomyosarcoma. The patient died thirty months after surgical resection without evidence of cardiac recurrence. Although cardiac metastases from uterine leiomyosarcoma are exceptional, they should be suspected in the presence of suggestive symptoms, since they can be associated with long survival after surgical treatment.