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Related Experiment Videos

Long-term visual function and relative amblyopia in posterior persistent hyperplastic primary vitreous (PHPV).

Elisabeth Schulz1, Birgit Griffiths

  • 1Ophthalmology Clinic, Head and Skin Center, Eppendorf University Hospital, Hamburg, Germany. eschulz@uke.uni-hamburg.de

Strabismus
|June 9, 2006
PubMed
Summary

Early surgery and amblyopia treatment for persistent hyperplastic primary vitreous (PHPV) can lead to favorable long-term visual acuity (VA) outcomes, with minimal additional amblyopia.

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Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Surgical Ophthalmology

Background:

  • Persistent hyperplastic primary vitreous (PHPV) management has improved with surgical techniques.
  • However, functional results often remain in the low-vision range.

Purpose of the Study:

  • To report long-term visual acuity (VA) results.
  • To estimate relative amblyopia in early-operated PHPV patients.

Main Methods:

  • Six pediatric patients with PHPV underwent surgery (lentectomy +/- stalk-cutting) between 3-7 months old.
  • Post-operative pleoptic treatment was administered.
  • Visual acuity was assessed using Landolt rings and C-Tests up to 7-12 years of age.

Main Results:

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  • Good compliance with amblyopia treatment was observed in most patients.
  • Visual acuity improved up to early school age.
  • Final VA ranged from 0.1 to 0.7 with single optotypes; crowded optotype VA was only slightly lower.

    • Conclusions:

    • Early surgical intervention and amblyopia treatment for PHPV yield favorable long-term VA.
    • Minimal relative amblyopia suggests outcomes are primarily limited by ocular malformation severity.
    • Surgical treatment is encouraged for comparable PHPV cases.