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Updated: Jul 30, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
The Gore Excluder endograft device for the treatment of abdominal aortic aneurysms
S Sayeed1, L K Marone, M S Makaroun
1Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Insights
The Gore Excluder endograft offers a favorable alternative to open surgical repair for abdominal aortic aneurysms, with a history of clinical use since 1998. This review summarizes its effectiveness and application in endovascular aneurysm repair.
Area of Science:
- Vascular Surgery
- Endovascular Techniques
- Medical Device Technology
Background:
- Open surgical repair of abdominal aortic aneurysms (AAA) is a long-established procedure.
- Despite advancements, open AAA repair remains associated with significant complications.
- Endovascular aneurysm repair (EVAR) has emerged as an alternative treatment modality.
Purpose of the Study:
- To review the clinical use of the Gore Excluder endograft.
- To trace the device's history from its initial clinical trial to its current commercial status.
- To evaluate the Excluder endograft's performance in AAA treatment.
Main Methods:
- Review of clinical trial data and commercial use of the Gore Excluder endograft.
- Comparison of endovascular repair with open surgical repair for AAAs.
- Analysis of outcomes and complications associated with the Excluder endograft.
Main Results:
- The Gore Excluder endograft is a third-generation device approved in the United States.
- Multiple trials have compared the Excluder endograft to open repair, demonstrating favorable outcomes.
- The device has been in clinical use since its initial trial in 1998.
Conclusions:
- The Gore Excluder endograft represents a significant advancement in AAA treatment.
- Endovascular repair with the Excluder device offers a viable alternative to open surgery.
- Continued evaluation of long-term outcomes is essential for optimizing EVAR strategies.
Unlabelled:
Open surgical repair on abdominal aortic aneurysms has been performed for many years with good
Results:
Despite the many advances in medical care, the procedure is still associated with many complications. The Gore Excluder endograft is a third-generation endograft that became the third commercially available endograft approved in the United States. Data from multiple trials have compared the use of the Excluder endograft to open repair and have shown favorable
Results:
This review shall summarize the clinical use of the Excluder endograft from its initial clinical trial in 1998 to its current commercial use.
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