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Updated: Aug 7, 2026

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Observing S-phase dynamics of histone modifications with fluorescently labeled antibodies
Rong Wu1, Anna V Terry, David M Gilbert
1Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY, USA.
Abstract:
Histone modifications are central to epigenetic regulation and must be reestablished with each round of DNA replication. Here we describe methods to localize these modifications within mammalian nuclei and to relate them to specific spatiotemporal patterns of DNA replication.
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