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Small cell carcinoma of the ovary presenting as bone marrow metastasis: a rare presenting feature

Uma Nahar Saikia1, P Malhotra, N Khandelwal

  • 1Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh. umasakia@yahoo.com

Indian Journal of Pathology & Microbiology
|June 10, 2006
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...