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Factor XIII-deficiency in the blood of venous leg ulcer patients

W Vanscheidt1, K Hasler, H Wokalek

  • 1Department of Dermatology, University of Freiburg, FRG.

Acta Dermato-Venereologica
|January 1, 1991
PubMed

Pericapillary fibrin cuffs are probably involved in the pathogenesis of venous leg ulcers. Factor XIII (Fibrin stabilizing factor) is of importance in wound healing. Its activity, which may affect ulceration, was found to be significantly reduced in the blood of venous leg ulcer patients and in post-phlebitic patients, compared with healthy controls.

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