Related Experiment Videos
[Glucose levels in non-diabetic patients. Is it a prognostic factor in acute coronary syndrome?]
L Fácila1, V Bertomeu-González, J Sanchís
1Servicio de Cardiología, Consorcio Hospitalario Provincial de Castellón, Castellón, España. lfacila@hotmail.com
Introduction:
The role of glucose elevation above levels considered normal in non- diabetic patients with acute coronary syndromes (ACS) is not adequately defined. The aim of this study was to determine the association between serum glucose at admission and 1-year mortality in this type of patients.
Methods:
We studied 648 non diabetic patients admitted consecutively with ACS. Serum glucose was determined at admission, together with classical risk factors, biochemical and inflammatory markers. The primary endpoint was all cause mortality at one year follow-up.
Results:
Patients with normal glucose had lower mortality than patients with impaired fasting glucose (14.1% vs 5.7% 1-year mortality) or with glucose levels in diabetic range (24.7% vs 5.7% 1-year mortality).
Conclusions:
In non-ST elevation acute coronary syndromes, elevated levels of glucose in non-diabetic patients are strong predictors of all cause death at one year follow-up. This prognostic value is independent of other risk factors biochemical and inflammatory markers.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Hyperglycemia
Hypoglycemia and Glucagon
Acute Coronary Syndrome I: Introduction
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis