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Related Experiment Videos

Benzodiazepines: abuse and new use.

L B Warneke1

  • 1University of Alberta, Department of Psychiatry, Edmonton.

Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
|April 1, 1991
PubMed
Summary

Benzodiazepines are safe and have low abuse potential when prescribed correctly. This review covers their uses, risks, and safe prescribing practices for conditions like panic disorder.

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Area of Science:

  • Pharmacology and Therapeutics
  • Psychiatry

Background:

  • Benzodiazepines are widely prescribed medications.
  • Concerns exist regarding their potential for abuse and dependence.
  • Understanding their pharmacology is crucial for safe use.

Purpose of the Study:

  • To review the pharmacology of benzodiazepines.
  • To differentiate between abuse, rebound, recurrence, and withdrawal.
  • To explore new therapeutic applications and provide guidance on rational prescribing.

Main Methods:

  • Literature review of benzodiazepine pharmacology and clinical use.
  • Analysis of data on benzodiazepine abuse and dependence.
  • Examination of evidence for new indications.

Main Results:

  • Benzodiazepines are generally safe with negligible abuse potential when used appropriately.
  • Dangers of alternatives like alcohol and barbiturates are highlighted.
  • New uses include panic disorder, mania, and psychotic states.

Conclusions:

  • Rational prescribing and careful monitoring are essential for benzodiazepine therapy.
  • The perception of benzodiazepines as inherently dangerous and addictive is discouraged.
  • Emphasize the safety profile when used for appropriate indications.

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