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[Effect of maternal autoimmune thyroid disease on intellectual development of infants]

Hong Zhu1, Hua-qing Mao, Li-qin Chen

  • 1Department of Endocrinology, The Affiliated Children's Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. chkjk@zju.edu.cn

Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences
|June 10, 2006
PubMed

Insights

Maternal Hashimoto's disease can impact infant thyroid function and development. Infants born to mothers with this autoimmune thyroid condition showed developmental delays compared to those born to healthy mothers.

Area of Science:

  • Endocrinology
  • Developmental Pediatrics
  • Immunology

Context:

  • Maternal autoimmune thyroid disease, specifically Hashimoto's disease, is a growing concern.
  • The impact on neonatal outcomes requires further investigation.
  • Understanding these effects is crucial for early intervention.

Purpose:

  • To investigate the effects of maternal Hashimoto's disease on infant thyroid function.
  • To assess the impact on intellectual and psychomotor development in infants.
  • To compare developmental outcomes with infants of healthy mothers.

Summary:

  • A cohort of 21 infants born to mothers with Hashimoto's disease was studied.
  • Infant thyroid function revealed abnormalities including hyperthyrotropinemia and congenital hypothyroidism.
  • Infants exhibited delayed mental and psychomotor development compared to controls (P <0.05).

Impact:

  • Maternal Hashimoto's disease poses risks to infant thyroid health.
  • Potential for long-term neurodevelopmental consequences in affected infants.
  • Highlights the need for maternal thyroid screening and infant monitoring.
Abstract

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