Related Experiment Video
Updated: Aug 7, 2026

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
Published on: September 22, 2017
Cardiopulmonary bypass surgery in a patient with paroxysmal nocturnal haemoglobinuria
D Dinesh1, B Baker, J M Carter
1New Zealand Blood Service, Wellington, New Zealand. dorothy.dinesh@nzblood.co.nz
Abstract:
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare acquired haemolytic anaemia. Cardiac bypass surgery in patients with PNH may be complicated by aggravation of haemolysis in addition to increased risk of infection, renal failure, bleeding and thrombosis. We describe a case of uncomplicated cardiopulmonary bypass surgery for aortic valve replacement and aortoplasty in a patient with PNH and discuss some recommendations to reduce the risk of peri-operative complications.
Related Concept Videos
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Cardiomyopathy VII: Pre and Post Operative Nursing Management

