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Updated: Aug 7, 2026

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 8, 2024
Clinical results of sole therapy TMR treatment
1Cardiothoracic Surgery Research Program, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA. khorvath@nih.gov
Abstract:
The safety and efficacy of transmyocardial laser revascularization (TMR) is best demonstrated by the data collected from several multi-institutional randomized controlled trials. These trials are an important link between the preclinical data and the most common use of TMR (TMR + Coronary Artery Bypass Grafting). In addition to significant symptomatic relief both short- and long-term objective data were also garnered in these studies. A review of the history, study design, and outcomes is provided.

