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Effects of ginsenoside-Rb2 on adenine nucleotide content of rat hepatic tissue
T Yokozawa1, N Fujitsuka, T Yasui
1Department of Applied Biochemistry, Toyama Medical and Pharmaceutical, Japan.
The Journal of Pharmacy and Pharmacology
|April 1, 1991
Abstract:
In comparison with non-diabetic rats, the tissue ATP content of diabetic rats is lower and the AMP content higher. However, daily intraperitoneal administration of ginsenoside-Rb2 for several days resulted in an increase of tissue ATP content and a decrease of AMP content, characterized by an increase in the adenine nucleotide content, as well as improvement of energy charge. Thus, ginsenoside-Rb2 administration caused a change in the pattern of metabolism, activating the ATP supply system.