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[Cancer-related pain].
Lena E Lundorff1, Jørgen Eriksen, Per Sjøgren
1Herning Sygehus, Palliativt Team, og H:S Rigshospitalet, Tvaerfagligt Smertecenter, København Ø.
Ugeskrift for Laeger
|June 14, 2006
Summary
Opioid analgesics manage cancer pain, but newer side effects like cognitive impairment and allodynia emerge. Spinal analgesia offers an alternative when oral opioids become ineffective.
Area of Science:
- Oncology
- Pain Management
- Pharmacology
Context:
- Pain is a severe symptom in cancer patients.
- Opioid analgesics are the primary treatment for cancer pain.
- Methadone is an emerging alternative to morphine, potentially increasing in potency with opioid exposure.
Purpose:
- To discuss opioid analgesics in cancer pain management.
- To highlight newer opioid side effects.
- To present alternative pain management strategies.
Summary:
- Opioid analgesics are crucial for cancer pain, but patients may experience "newer" side effects such as cognitive impairment and allodynia.
- Methadone is gaining attention as an alternative to morphine, with evidence suggesting increased potency after prior opioid exposure.
- When oral opioids fail, advanced methods like spinal analgesia can provide effective pain relief.
Impact:
- Provides insights into advanced opioid therapy for cancer pain.
- Highlights the importance of monitoring for "newer" opioid side effects.
- Informs clinicians about alternative pain management options when oral opioids are insufficient.