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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Arthritis progression after patellofemoral joint replacement
Steve G Nicol1, Jeremy M Loveridge, A E Weale
1Winford Unit, Avon Orthopaedic Centre, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB, UK. sgnicol@doctors.net.uk
The Knee
|June 14, 2006
Summary
Revision surgery after patellofemoral joint replacement (PFJR) is often needed for tibiofemoral osteoarthritis (OA). Patients with pre-existing trochlear dysplasia had fewer OA issues, indicating they are ideal PFJR candidates.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Radiology
Background:
- Patellofemoral joint replacement (PFJR) is an option for specific knee osteoarthritis cases.
- Progressive tibiofemoral osteoarthritis (OA) can necessitate revision surgery after PFJR.
- Understanding failure modes is crucial for optimizing PFJR outcomes.
Purpose of the Study:
- To quantify the incidence of tibiofemoral OA progression after PFJR.
- To identify risk factors for developing tibiofemoral OA post-PFJR.
- To evaluate the suitability of PFJR for patients with trochlear dysplasia.
Main Methods:
- Prospective study of 103 patients undergoing PFJR.
- Mean follow-up of 7.1 years.
- Radiographic assessment of tibiofemoral OA progression and measurement of preoperative sulcus angles for trochlear dysplasia.
Main Results:
- 14% of knees required revision, with 12% due to tibiofemoral OA.
- Radiographic tibiofemoral OA progression occurred in 7% of medial compartments over a mean of 51 months.
- Revision for tibiofemoral OA was significantly less common in patients with preoperative trochlear dysplasia (0% revised) compared to those without (17% revised).
Conclusions:
- Progressive tibiofemoral OA is a significant cause of failure after PFJR.
- Preoperative trochlear dysplasia is associated with a lower risk of developing tibiofemoral OA post-PFJR.
- Patients with patellofemoral arthritis secondary to trochlear dysplasia are ideal candidates for PFJR.