Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Asian experience with the Pintucci keratoprosthesis.

Quresh B Maskati1, B T Maskati

  • 1Maskati Eye Clinic, Mumbai, India. qureshmaskati@gmail.com

Indian Journal of Ophthalmology
|June 14, 2006
PubMed
Summary

The Pintucci Biointegrable Keratoprosthesis (PBIKP) offers improved vision for many bilaterally blind Asian patients unsuitable for traditional corneal transplants. Careful selection is key to its success, with few severe complications reported.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Video display terminals - A wake-up call.

Indian journal of ophthalmology·2021
Same author

All India Ophthalmological Society - Eye Bank Association of India consensus statement on guidelines for cornea and eyebanking during COVID-19 era.

Indian journal of ophthalmology·2020
Same author

The journey of keratoprosthesis in India.

Indian journal of ophthalmology·2018
Same author

Prevalence of diabetic retinopathy in India: The All India Ophthalmological Society Diabetic Retinopathy Eye Screening Study 2014.

Indian journal of ophthalmology·2016
Same author

The unique problem of glaucoma: under-diagnosis and over-treatment.

Indian journal of ophthalmology·2010
Same author

Collagen cross-linkage with riboflavin by Dr. Vinay Agarwal.

Indian journal of ophthalmology·2010

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Corneal blindness significantly impacts quality of life, especially in Asian populations.
  • Conventional treatments like keratoplasty often fail in complex cases, including chemical burns and severe dry eye.
  • The Pintucci Biointegrable Keratoprosthesis (PBIKP) presents an alternative for patients with otherwise untreatable corneal conditions.

Purpose of the Study:

  • To evaluate the outcomes of the Pintucci Biointegrable Keratoprosthesis (PBIKP) in a cohort of Asian patients.
  • To assess the efficacy and safety of PBIKP implantation for severe corneal blindness.
  • To identify potential complications and success rates associated with PBIKP in a diverse patient group.

Main Methods:

  • A retrospective analysis was conducted on 31 eyes of 31 consecutive patients who received PBIKP implantation.

Related Experiment Videos

  • Patients included those with chemical burns, failed grafts, severe dry eye, and other complex corneal pathologies.
  • Follow-up ranged from 6 months to 7 years, with a mean of 3.2 years, assessing visual outcomes and complications.

    • Main Results:

    • Twenty-four out of 31 eyes (77%) achieved visual improvement beyond finger counting at 1.5 meters, enabling independent function.
    • Four eyes (13%) improved to 20/200 or better visual acuity.
    • No cases of infection or retroprosthetic membrane were observed; 12 eyes experienced complications, but few were vision-threatening.

    Conclusions:

    • The Pintucci Biointegrable Keratoprosthesis (PBIKP) demonstrates potential as a valuable treatment option for bilateral corneal blindness in Asian patients.
    • Careful patient selection is crucial for optimizing outcomes with PBIKP.
    • PBIKP offers a viable solution for individuals unresponsive to conventional medical and surgical interventions for corneal disease.