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Ambiguous genitalia
Ricardo González1, Lisandro A Piaggio
1Division of Urology, Alfred I. duPont Hospital for Children, Nemours Children's Clinic, Wilmington, Delaware 19899, USA. rgonzale@nemours.org
Current Opinion in Urology
|June 14, 2006
Summary
Surgery for female pseudohermaphroditism remains controversial. Continued development of refined surgical techniques is favored to improve outcomes for congenital adrenal hyperplasia patients undergoing feminizing genitoplasty.
Area of Science:
- Pediatric Surgery
- Endocrinology
- Genetics
Background:
- Female pseudohermaphroditism, often associated with congenital adrenal hyperplasia, presents complex challenges in gender assignment and surgical reconstruction.
- Surgical interventions for female genital reconstruction aim to align anatomy with gender identity but involve significant technical and timing considerations.
Purpose of the Study:
- To review surgical management of female pseudohermaphroditism published since 2004.
- To address current controversies regarding the timing and techniques of female genital reconstruction.
Main Methods:
- Systematic review of nine relevant articles published between 2004 and the present.
- Analysis of surgical techniques, outcomes, voiding function, and timing of interventions.
Main Results:
- Included studies cover diverse surgical techniques and patient cohorts.
- Short-term and long-term results, including voiding function, were evaluated.
Conclusions:
- Past surgical outcomes for congenital adrenal hyperplasia, when evaluated in adulthood, have been suboptimal.
- Continued refinement of surgical techniques is recommended to improve future reconstructive outcomes for this condition.