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Published on: April 3, 2014

Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase

Jason D Fowler1, Zucai Suo

  • 1Department of Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA.

Chemical Reviews
|June 15, 2006
PubMed
Abstract

No abstract available in PubMed .

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One of the unique features of tRNA is the presence of modified bases. In some tRNAs, modified bases account for nearly 20% of the total bases in the molecule. Altogether, these unusual bases protect the tRNA from enzymatic degradation by RNases.
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