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Viral nanoparticles donning a paramagnetic coat: conjugation of MRI contrast agents to the MS2 capsid

Elizabeth A Anderson1, Steven Isaacman, David S Peabody

  • 1Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, USA.

Nano Letters
|June 15, 2006
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...