Zinc center as redox switch--new function for an old motif

Marianne Ilbert1, Paul C F Graf, Ursula Jakob

  • 1Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, 48109-1048, USA.

Summary

Reactive oxygen species and thiol-disulfide states regulate protein function. This review examines Hsp33 and RsrA, two redox-regulated proteins using cysteine-zinc centers as switches to control cellular stress responses.

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