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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Brain magnetic resonance imaging at 3 Tesla using BLADE compared with standard rectilinear data sampling.

Bernd J Wintersperger¹, Val M Runge, Jonmenjoy Biswas

¹Department of Clinical Radiology, University Hospitals-Grosshadern, Ludwig-Maximilians-University, Munich, Germany. Bernd.Wintersperger@med.uni-muenchen.de

Investigative Radiology

|June 15, 2006

Summary

This summary is machine-generated.

Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction (PROPELLER; BLADE) MRI significantly reduces motion and other artifacts in 3 T brain imaging, especially for axial T2-weighted FLAIR sequences. This technique offers improved image quality compared to standard k-space sampling.

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Area of Science:

Radiology
Medical Imaging
Neuroimaging

Background:

Standard k-space sampling in MRI can be prone to various imaging artifacts.
Artifacts can degrade image quality and potentially impact diagnostic accuracy.
The PROPELLER (BLADE) technique is an advanced acquisition method designed to mitigate artifacts.

Purpose of the Study:

To compare the Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction (PROPELLER; BLADE) technique against standard k-space sampling for brain MRI at 3 Tesla.
To evaluate the reduction of specific imaging artifacts, such as motion and pulsation artifacts, in both axial and sagittal orientations.
To assess the overall image quality and diagnostic utility of PROPELLER (BLADE) compared to conventional methods.

Main Methods:

A prospective study involving 40 consenting patients was conducted at 3 T.
Standard and PROPELLER (BLADE) techniques were compared for axial T2-weighted FLAIR and sagittal T1-weighted gradient echo sequences.
Imaging protocols were matched for spatial resolution, and data were evaluated by two experienced neuroradiologists for artifacts and overall quality.

Main Results:

PROPELLER (BLADE) axial T2-weighted FLAIR demonstrated significantly fewer pulsation and Gibb's artifacts than standard scans.
Ghosting (motion) artifacts were substantially lower in PROPELLER T2-weighted data, with readers rating it superior or equal in 95% of cases (kappa = 1).
Sagittal T1-weighted PROPELLER FLAIR exhibited consistent wrap artifacts, with only fair reader agreement (kappa = 0.24).

Conclusions:

PROPELLER (BLADE) is a viable technique for 3 T brain MRI, effectively minimizing motion artifacts.
The PROPELLER acquisition scheme successfully reduces various artifacts that compromise scan quality.
While highly effective for axial T2-weighted imaging, further optimization may be needed for sagittal T1-weighted sequences to address wrap-around artifacts.