Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Noni juice is not hepatotoxic.

Brett-J West1, C-Jarakae Jensen, Johannes Westendorf

  • 1Research and Development Department, Tahitian Noni International, American Fork, UT 84003, USA. brett_west@tni.com

World Journal of Gastroenterology
|June 15, 2006
PubMed
Summary

Noni juice (Morinda citrifolia) is safe, with no evidence of liver toxicity found in clinical and animal studies. Reported cases of liver dysfunction are not supported by scientific data.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety and efficacy of dry grape extract when used as flavouring in water for drinking for all animal species and categories.

EFSA journal. European Food Safety Authority·2026
Same author

Safety and efficacy of a feed additive consisting of an extract from the dried leaves of <i>Hedera helix</i> L. (common ivy extract) and thymol for all animal species and categories except poultry, ornamental birds and all aquatic animal species (FEFANA asbl).

EFSA journal. European Food Safety Authority·2026
Same author

Safety and efficacy of a feed additive consisting of an essential oil derived from the flowering aerial parts of <i>Mentha arvensis</i> L. (cornmint oil) for use in all animal species (FEFANA asbl).

EFSA journal. European Food Safety Authority·2026
Same author

Safety and efficacy of a feed additive consisting of a proanthocyanidin-rich dry extract from the fruit of <i>Vaccinium macrocarpon</i> Aiton (cranberry extract) for dogs and cats (ACEL pharma S.r.l.).

EFSA journal. European Food Safety Authority·2026
Same author

Safety and efficacy of a feed additive consisting of an essential oil derived from the aerial parts of <i>Mentha spicata</i> L. (spearmint oil) for use in all animal species (FEFANA asbl).

EFSA journal. European Food Safety Authority·2025
Same author

Safety and efficacy of a feed additive consisting of an essential oil obtained from the flowering aerial parts of <i>Thymus vulgaris</i> L. and/or <i>Thymus zygis</i> L. (thyme oil) for use in all animal species (FEFANA asbl).

EFSA journal. European Food Safety Authority·2025

Area of Science:

  • Food safety
  • Toxicology
  • Hepatology

Background:

  • Noni juice (Morinda citrifolia) is approved in the EU.
  • Concerns about potential liver toxicity linked to anthraquinones have been raised.
  • Three cases of acute hepatitis in noni juice consumers were published suggesting a causal link.

Purpose of the Study:

  • To evaluate the safety of noni juice, specifically its potential for liver toxicity.
  • To investigate the toxicological significance of M. citrifolia anthraquinones.

Main Methods:

  • Human clinical safety study measuring liver function.
  • Subacute and subchronic animal toxicity tests.
  • Chemical structure analysis of M. citrifolia anthraquinones.

Main Results:

  • No evidence of adverse liver effects in human studies, even at high doses.
  • Animal toxicity tests showed no liver damage.
  • M. citrifolia anthraquinones are present in negligible amounts and lack toxic chemical structures.

Conclusions:

  • Available data indicates noni juice does not cause liver toxicity.
  • Reported cases of hepatitis are not supported by toxicological evidence.
  • Noni juice is considered safe for consumption.

Related Experiment Videos