Related Experiment Video
Updated: Aug 7, 2026
Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors
Published on: August 18, 2016
Radiological-pathological correlation in lipoblastoma and lipoblastomatosis
Shruti Moholkar1, Neil J Sebire, Derek J Roebuck
1Department of Radiology, Great Ormond Street Hospital, London, WC1N 3JH, UK.
Background:
Lipoblastoma and lipoblastomatosis are uncommon benign mesenchymal lesions that predominantly occur in infancy and early childhood.
Objective:
To evaluate the imaging and histological features of lipoblastoma and lipoblastomatosis.
Materials And Methods:
Retrospective review of the radiological and pathological findings in children with lipoblastoma and lipoblastomatosis treated at a single centre between 1997 and 2004.
Results:
Eight children (median age 18 months) had undergone imaging and surgery at our institution. An infiltrative growth pattern was identified at imaging in two children with lipoblastomatosis, and a well-defined mass in six children with lipoblastoma. In all patients, imaging showed a lesion composed mostly, but not entirely, of fat. There were no recurrences at follow-up of between 1 and 91 months.
Conclusion:
In infancy and early childhood, the identification of a tumour composed mostly of fat should suggest the diagnosis of lipoblastoma or lipoblastomatosis.