Related Experiment Videos
A randomized prospective study to compare ceftizoxime with cephradine as single dose prophylaxis in elective
D Skipper1, A P Corder, S J Karran
1University Surgical Unit, Southampton General Hospital.
The Journal of Hospital Infection
|April 1, 1991
Abstract:
This study compares the efficacy of ceftizoxime with that of cephradine as single agent prophylaxis in elective cholecystectomy. The incidence of purulent wound infection was low in both groups (ceftizoxime 1/99; cephradine 2/92). No adverse reactions to the trial antibiotics occurred in either group. Ceftizoxime is a safe, effective, convenient and well-tolerated antibiotic for use as single agent prophylaxis in elective cholecystectomy. However, because it has no demonstrable advantage over cephradine and is three times as expensive, its routine use is not justified.