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Updated: Aug 7, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Partitioning knowledge bases between advanced notification and clinical decision support systems
Tara Borlawsky1, Jianrong Li, Srikant Jalan
1Department of Biomedical Informatics, Columbia University, New York, NY, USA.
Abstract:
Due to the varying rates of change of ephemeral administrative and enduring clinical knowledge in decision support systems (DSSs), the functional partition of knowledge base (KB) components can lead to more efficient and cost-effective system implementation and maintenance. Our prototype loosely couples a clinical event monitor developed by Columbia University Medical Center (CUMC) with a secure notification service proxy developed by IBM Research to form a novel and complex clinical event communication service.
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