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Updated: Aug 7, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Risk for early-onset schizophrenia assessed via gray-matter distributions
1Regenstrief Institute, Inc. & Department of Radiology, University of Indiana School of Medicine, Indianapolis, IN, USA.
Abstract:
Automated image analysis algorithms were used to measure regional gray matter volumes in children with early-onset schizophrenia. Logistic regression analysis of gray matter volumes within Brodman areas was used to test the ability to predict whether a subject was normal or schizophrenic. The ROC area-under-the-curve was 0.84 +/- 0.15 across the 10 cross validation groups indicating good discrimination between schizophrenic and normal subjects.

