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Updated: Aug 7, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Decision support for community-based empirical antibiotic prescribing
Dana Teltsch1, David Pinelle, Nancy Winslade
1McGill University, Montreal, Quebec, Canada.
Abstract:
Inappropriate antibiotic prescribing is common, and the consequences are severe. Prescribing guidelines are intended to reduce inappropriate prescribing. Guidelines, though, give empirical antibiotic treatment recommendations that are general and not tailored to local prevalence patterns. A computerized decision support system for empirical antibiotic prescribing that considers the likely infectious organism, antibiotic susceptibility, and patient characteristics, should decrease inappropriate antibiotic prescribing. We describe the design of such a system and the setting for its evaluation.
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