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Cutaneous polyarteritis nodosa and ulcerative colitis.

G Chiu1, C N Rajapakse

  • 1Wellington Regional Rheumatology Unit, Hutt Hospital, New Zealand.

The Journal of Rheumatology
|May 1, 1991
PubMed
Summary
This summary is machine-generated.

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Necrotizing vasculitis rarely occurs with ulcerative colitis. This case details a patient with cutaneous polyarteritis nodosa 19 years after ulcerative colitis diagnosis and colectomy.

Area of Science:

  • Gastroenterology
  • Rheumatology
  • Dermatology

Background:

  • Ulcerative colitis (UC) is an inflammatory bowel disease.
  • Vasculitis, inflammation of blood vessels, is a rare complication of UC.

Observation:

  • A 48-year-old male with a history of UC presented with necrotizing vasculitis.
  • The patient had undergone total colectomy with rectal preservation 5 years prior.
  • The vasculitis affected small arteries in the skin and muscle.

Findings:

  • The presentation was consistent with cutaneous polyarteritis nodosa (PAN).
  • Cutaneous PAN has been previously associated with regional enteritis but not UC.
  • This represents a novel association between UC and cutaneous PAN.

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Implications:

  • This case expands the known spectrum of vasculitic complications in UC patients.
  • It highlights the importance of considering vasculitis in UC patients with new-onset skin and muscle symptoms.
  • Further research may elucidate sharedPathogenic mechanisms between UC and vasculitis.