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Updated: Aug 7, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
[Biological therapies of systemic lupus erythematosus]
Marzena Olesińska1, Hanna Chwalińska-Sadowska, Paweł Mielnik
1Instytut Reumatologii w Warszawie, Klinika Chorób Tkanki Lacznej. olesinska@ir.ids.pl
Abstract:
In recent years new potential therapies of systemic lupus erythematosus, called biological therapies, have been developed. These agents influence some immunological reactions, essential for genesis of systemic lupus erythematosus, ie. T cells and B cells activation, antibodies production, cytokines and complement components activation. Pathogenic basis of using these therapies, their safety and efficacy assessment have been presented.
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