Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Impact of automatic threshold capture on pulse generator longevity.

Ruo-han Chen1, Ke-ping Chen, Fang-zheng Wang

  • 1Centre of Arrhythmia Diagnosis and Treatment, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

Chinese Medical Journal
|June 20, 2006
PubMed
Summary

AutoCapture (AC) significantly extends pacemaker longevity by optimizing energy use. This pacing algorithm is especially beneficial for patients requiring higher pacing thresholds, improving battery life.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adrenomedullin improved endothelial dysfunction via receptor-Akt pathway in rats with obesity-related hypertension.

Hypertension research : official journal of the Japanese Society of Hypertension·2024
Same author

C and G are frequently mutated into T and A in coding regions of human genes.

Molecular genetics and genomics : MGG·2024
Same author

Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.

International journal of molecular sciences·2023
Same author

Adrenomedullin in paraventricular nucleus attenuates adipose afferent reflex and sympathoexcitation via receptors mediated nitric oxide-gamma-aminobutyric acid A type receptor pathway in rats with obesity-related hypertension.

Journal of hypertension·2022
Same author

Identification and Validation of Common Reference Genes for Normalization of Esophageal Squamous Cell Carcinoma Gene Expression Profiles.

BioMed research international·2022
Same author

Heterogeneity of immune control in chronic hepatitis B virus infection: Clinical implications on immunity with interferon-α treatment and retreatment.

World journal of gastroenterology·2022

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Device Technology
  • Electrophysiology

Background:

  • The St. Jude Medical AutoCapture (AC) algorithm automatically verifies ventricular capture beat-by-beat.
  • AC was presumed to enhance pacemaker longevity and safety through energy conservation.
  • This study aimed to quantify the longevity benefits of AC compared to manual programming.

Purpose of the Study:

  • To estimate the extension in pacemaker longevity provided by the AutoCapture (AC) algorithm.
  • To compare the longevity of AC-enabled pacemakers with those using manually optimized or nominal output settings.
  • To evaluate the efficacy of AC in patients with varying chronic pacing thresholds.

Main Methods:

  • Thirty-four patients with St. Jude Affinity series pacemakers were studied.

Related Experiment Videos

  • Ventricular output was programmed under three conditions: AC on, AC off (nominal output), and AC off (optimized output).
  • Measurements included thresholds, lead impedance, evoked responses, and battery current drain; patients were grouped by chronic threshold (>1V or <1V).

    • Main Results:

    • Current drain was significantly lower with AC on (14.33 mA) compared to nominal (18.4 mA) or optimized (16.74 mA) settings (P < 0.01).
    • Estimated pacemaker longevity was significantly extended with AC on (103 months) versus nominal settings (80 months) (P < 0.01).
    • AC demonstrated extended longevity benefits compared to optimized programming, particularly in patients with pacing thresholds above 1 V.

    Conclusions:

    • AutoCapture (AC) technology can significantly prolong pacemaker longevity.
    • The benefits of AC are most pronounced in patients with higher pacing thresholds.
    • AC offers an energy-saving and effective pacing strategy, enhancing device longevity.