Related Experiment Video

Updated: Aug 7, 2026

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

Emerging evidence for the neuroprotective role of alpha-synuclein

Hyoung-gon Lee1, Xiongwei Zhu, Atsushi Takeda

  • 1Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.

Experimental Neurology
|June 20, 2006
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
09:16

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

Published on: June 26, 2018

Related Experiment Videos

Last Updated: Aug 7, 2026

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
09:16

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

Published on: June 26, 2018

Related Concept Videos

Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
Parkinson Disease ll: Pathophysiology01:24

Parkinson Disease ll: Pathophysiology

Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...

Articles linked to this work by shared authors, journal, and citation graph.

Neddylation-dependent RAB40-Cullin5 E3 ligase complex controls ubiquitin-mediated proteasomal degradation of DNAJC13.

BBA advances·2026

Safety and efficacy of the anti-α-synuclein monoclonal antibody amlenetug for the treatment of patients with multiple system atrophy (AMULET): a phase 2, randomised, double-blind, multicentre trial.

The Lancet. Neurology·2026

Nocturnal hypercapnia in the patients with idiopathic interstitial pneumonia registered for lung transplantation.

Respiratory investigation·2026

Temporal patterns of motor and nonmotor symptom emergence in Parkinson's disease: a cluster analysis.

Clinical parkinsonism & related disorders·2026

[Psychiatric Symptoms in Parkinson's Disease: Epidemiology, Pathophysiology, and Therapeutic Strategies].

Brain and nerve = Shinkei kenkyu no shinpo·2026

CRISPR/Cas9-Mediated Knockouts of the ALG3 and GNTI in N. benthamiana and Their Application to Pharmaceutical Production.

Plant biotechnology journal·2025

Functional reorganization after traumatic brain injury: A group ICA-based resting-state fMRI study in a porcine model.

Experimental neurology·2026

Investigation of the predictive value of routine electroencephalogram compared to continuous electroencephalogram in the acute phase of traumatic brain injury.

Experimental neurology·2026

Therapeutic hypothermia does not prevent dysmaturity of medial ganglionic eminence-derived interneurons in the dorsal hippocampus after neonatal hypoxia-ischemia.

Experimental neurology·2026

Repeated hyperbaric oxygen exposure increases seizure susceptibility despite GABAergic modulation and is associated with mitochondrial and transcriptional adaptations.

Experimental neurology·2026

Oleic acid ameliorates the disrupted blood-brain barrier and neuroinflammation following intracerebral hemorrhage in mice by regulating PPARγ.

Experimental neurology·2026

Adaptive reweighting of synaptic and intrinsic excitability by deep brain stimulation in a dystonia model.

Experimental neurology·2026

Low-dose N-methyl-D-aspartate protects against amyloid-β-induced neurotoxicity by suppressing the MLK3-MKK7-JNK3 pathway and activating the PI3K-PDK1-Akt pathway.

Neuroreport·2026

Safety and Efficacy of Using Sugammadex in Pediatric Patients: A Narrative Review.

Journal of pain research·2026

Unveiling Functional Architecture of Human Thalamus: AStereoelectroencephalography Study.

MedComm·2026

Sleep dependent autonomic correlates of affect and arousal in younger and older adults.

Sleep advances : a journal of the Sleep Research Society·2026

NEAT1 modulates neutrophil functions via glycolysis to restrain mucosal inflammation in ulcerative colitis.

Frontiers in immunology·2026

Changes in serum sodium during an external ventricular drain weaning in patients with subarachnoid hemorrhage.

Frontiers in neurology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us