Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Linearization and Approximation01:26

Linearization and Approximation

31
Linearization is a mathematical technique used to approximate complex, nonlinear functions with simpler linear models in the vicinity of a chosen reference point. The method is based on the idea that, although a function may be difficult to evaluate exactly, its behavior near a specific input value can often be closely approximated by the tangent line at that point. This approach is particularly useful when small deviations from a known value are involved.Consider the square root function, for...
31
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

3.1K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
3.1K
Linear Circuits01:17

Linear Circuits

832
A linear circuit is characterized by its output having a direct proportionality to its input, adhering to the linearity property, which encompasses the principles of homogeneity (scaling) and additivity. Homogeneity dictates that when the input, also referred to as the excitation, is multiplied by a constant factor, the output, known as the response, is correspondingly scaled by the same constant factor. For instance, if the current is multiplied by a constant 'k,' the voltage likewise...
832
Linear Momentum00:55

Linear Momentum

17.6K
The term momentum is used in various ways in everyday language, most of which are consistent with the precise scientific definition. Generally, momentum implies a tendency to continue on course—to move in the same direction; we tend to speak of sports teams or politicians gaining and maintaining the momentum to win.  Momentum is also associated with great mass and speed and is often considered when talking about collisions. For example, when rugby players collide and fall to the...
17.6K
Molecular Orbital Theory I02:35

Molecular Orbital Theory I

47.0K
Overview of Molecular Orbital Theory
47.0K
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

45.4K
VSEPR Theory for Determination of Electron Pair Geometries
45.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kinetic Insights into Cholera Toxin B-Biomimetic Glycan Interactions.

Biomacromolecules·2026
Same author

Pharmacologic properties and inhibitory activity of 6-azasteroids against <i>Mycobacterium leprae in vivo</i> and <i>in vitro</i>.

Microbiology spectrum·2025
Same author

Vacuum electrospray deposition for face-on orientation and interface preservation in organic photovoltaics.

Scientific reports·2025
Same author

<i>Mycobacterium tuberculosis</i> Mce3R TetR-like Repressor Forms an Asymmetric Four-Helix Bundle and Binds a Nonpalindrome Sequence†.

ACS chemical biology·2024
Same author

Glycopolymers Prepared by Alternating Ring-Opening Metathesis Polymerization Provide Access to Distinct, Multivalent Structures for the Probing of Biological Activity.

ACS bio & med chem Au·2024
Same author

Triblock Glycopolymers with Two 10-mer Blocks of Activating Sugars Enhance the Activation of Acrosomal Exocytosis in Mouse Sperm.

ACS bio & med chem Au·2024

Related Experiment Video

Updated: Jan 20, 2026

Manipulating Living Cells to Construct Stable 3D Cellular Assembly Without Artificial Scaffold
07:09

Manipulating Living Cells to Construct Stable 3D Cellular Assembly Without Artificial Scaffold

Published on: October 26, 2018

6.6K

Romping the cellular landscape: linear scaffolds for molecular recognition.

Younjoo Lee1, Nicole S Sampson

  • 1Department of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA.

Current Opinion in Structural Biology
|June 20, 2006
PubMed
Summary

Researchers are developing advanced linear polymers for precise cell surface mapping. These multivalent molecules offer new possibilities for controlling cellular signaling, drug delivery, and tissue imaging applications.

More Related Videos

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
09:28

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

8.5K
Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis
08:46

Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis

Published on: September 16, 2014

8.2K

Related Experiment Videos

Last Updated: Jan 20, 2026

Manipulating Living Cells to Construct Stable 3D Cellular Assembly Without Artificial Scaffold
07:09

Manipulating Living Cells to Construct Stable 3D Cellular Assembly Without Artificial Scaffold

Published on: October 26, 2018

6.6K
Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
09:28

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

8.5K
Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis
08:46

Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis

Published on: September 16, 2014

8.2K

Area of Science:

  • Biomaterials Science
  • Molecular Biology
  • Cell Biology

Background:

  • Multivalent molecules with specific recognition elements are crucial for mapping cell surface topology.
  • Applications include cellular signaling control, drug delivery, and tissue imaging.
  • Linear polymers offer a versatile scaffold for designing such molecules.

Purpose of the Study:

  • To explore the development of synthetic approaches for creating linear polymers with controlled lengths and recognition element spacing.
  • To advance the design of surface-mapping molecules for biological applications.

Main Methods:

  • Development of novel synthetic strategies for linear polymer construction.
  • Precise control over polymer length and the spatial arrangement of recognition elements.

Main Results:

  • Successful synthesis of linear polymeric substrates with highly controlled characteristics.
  • Demonstrated potential for creating precisely arrayed recognition elements on a polymer scaffold.

Conclusions:

  • Advances in synthetic chemistry enable the creation of sophisticated linear polymers for cell surface characterization.
  • These tailored polymers hold significant promise for diverse biomedical applications, including targeted therapies and diagnostics.