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The impact of hypertension on systolic and diastolic left ventricular function. A tissue Doppler echocardiographic

Manolis Bountioukos1, Arend F L Schinkel, Jeroen J Bax

  • 1Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands.

American Heart Journal
|June 20, 2006
PubMed

Insights

Hypertension significantly impacts heart function, causing combined systolic and diastolic impairments even with preserved global systolic function. Echocardiography reveals these subtle changes in hypertensive patients.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Hypertension Research

Background:

  • Hypertension is a prevalent condition affecting cardiovascular health.
  • Assessing its impact on cardiac function is crucial for patient management.
  • Echocardiography offers valuable insights into cardiac mechanics.

Purpose of the Study:

  • To evaluate the effects of hypertension on systolic and diastolic left ventricular (LV) function.
  • To utilize 2D echocardiography, Doppler, and tissue Doppler imaging (TDI) for comprehensive assessment.
  • To identify specific echocardiographic markers of cardiac dysfunction in hypertensive individuals.

Main Methods:

  • A cohort of 414 outpatients underwent detailed echocardiographic assessments.
  • Systolic and diastolic LV function parameters were analyzed using conventional Doppler and TDI.
  • Patients were categorized based on the presence or absence of systemic hypertension (BP ≥ 140/90 mmHg or on medication).

Main Results:

  • Complete echocardiograms were obtained from 397 patients; 68% had hypertension.
  • Hypertensive patients exhibited increased LV mass index and relative wall thickness.
  • Lower TDI peak systolic velocity (V(S)) and impaired diastolic function indices were observed in hypertensive individuals.

Conclusions:

  • Quantitative echocardiography with TDI demonstrates that hypertensive patients often have combined systolic and diastolic dysfunction.
  • These impairments can exist despite preserved global LV systolic function.
  • TDI is effective in revealing subtle cardiac functional changes associated with hypertension.
Abstract

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