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Synthesis of aromatic C-xylosides by position inversion of glucose
Jesper Malmberg1, Katrin Mani, Elin Säwén
1Organic Chemistry, Lund University, PO Box 124, SE-221 00 Lund, Sweden.
Abstract:
Two formally C-xylosylated analogs to 2-naphthyl beta-D-xylopyranoside, which is known to initiate priming of glucosaminoglycan chains, were synthesized by a position inversion of glucose (i.e., position 1 becomes position 5). The D-C-xyloside showed priming, while the L-C-xyloside did not initiate priming.
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