Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lupus-associated pancreatitis.

Gabriel S Breuer1, Asher Baer, David Dahan

  • 1Department of Internal Medicine, Shaare-Zedek Medical Center, P.O. Box 3235, Jerusalem 91031, Israel. gbreuer@szmc.org.il

Autoimmunity Reviews
|June 20, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hyperuricemia and Adverse Outcomes in Patients Hospitalized for COVID-19 Disease.

Clinical medicine & research·2023
Same author

Intracerebral Calcification in Sjögren's Syndrome.

The Israel Medical Association journal : IMAJ·2023
Same author

A deep look into the storm: Israeli multi-center experience of coronavirus disease 2019 (COVID-19) in patients with autoimmune inflammatory rheumatic diseases before and after vaccinations.

Frontiers in immunology·2023
Same author

Optic Nerve Inflammation Associated with Severe Acute Respiratory Syndrome Coronavirus 2.

The Israel Medical Association journal : IMAJ·2023
Same author

Management Options for Linear Scleroderma ("En Coup de Sabre").

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2022
Same author

Intravenous Alpha-1 Antitrypsin Therapy for Critically Ill COVID-19 Patients.

The Israel Medical Association journal : IMAJ·2022
Same journal

Decoding gut microbiome alterations in celiac disease: Implications for pathogenesis and treatment.

Autoimmunity reviews·2026
Same journal

Rethinking immunosuppression in limited cutaneous systemic sclerosis. The lcSSc conundrum; pros and cons for a timely immunosuppressive treatment.

Autoimmunity reviews·2026
Same journal

Kidney failure in patients with ANCA-associated vasculitis: A systematic review of outcomes.

Autoimmunity reviews·2026
Same journal

The role of antimicrobial peptides in rheumatoid arthritis: From mucosal predisposition to chronic synovitis.

Autoimmunity reviews·2026
Same journal

The role of short-chain fatty acids as key mediators of gut microbiota - host crosstalk in thyroid diseases.

Autoimmunity reviews·2026
Same journal

Intermittent hydrarthrosis (periodic synoviosis): A narrative review.

Autoimmunity reviews·2026
See all related articles

Lupus patients can experience acute pancreatitis unrelated to common causes. This rare condition, lupus-associated pancreatitis, has a high mortality rate, but steroid treatment may reduce it.

Area of Science:

  • Rheumatology
  • Gastroenterology
  • Internal Medicine

Background:

  • Systemic lupus erythematosus (SLE) can manifest with various organ involvements.
  • Acute pancreatitis is a rare but serious complication in lupus patients.
  • Lupus-associated pancreatitis is distinct from pancreatitis due to mechanical obstruction or toxic-metabolic factors.

Purpose of the Study:

  • To investigate the characteristics, incidence, and outcomes of acute pancreatitis in lupus patients.
  • To identify factors associated with mortality in lupus-associated pancreatitis.
  • To evaluate the impact of steroid treatment on mortality.

Main Methods:

  • A literature search was conducted to identify cases of lupus-associated pancreatitis.
  • Data from 77 lupus patients with pancreatitis were analyzed.

Related Experiment Videos

  • Statistical analysis was performed to determine associations with mortality.

    • Main Results:

    • The estimated annual incidence of lupus-associated pancreatitis is 0.4-1.1/1000 lupus patients.
    • Abdominal pain was the most common symptom (88%), and diagnosis relied on elevated serum amylase/lipase (97%).
    • Mortality was 27%, significantly higher than in non-SLE pancreatitis, with active lupus and biochemical abnormalities linked to increased risk.

    Conclusions:

    • Acute pancreatitis is a rare but severe complication in lupus patients, often occurring during active disease.
    • Active lupus and biochemical abnormalities are associated with higher mortality.
    • Steroid treatment demonstrated a 67% reduction in mortality compared to non-treated patients.