Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Building chromosome-wide LD maps.

María M Abad-Grau¹, Rosana Montes, Paola Sebastiani

¹Software Engineering Department, University of Granada Granada 18071, Spain.

Bioinformatics (Oxford, England)

|June 20, 2006

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Resampling-Based Framework for Network Structure Learning in High-Dimensional Data.

ArXiv·2026

Same author

Genetic associations with longevity in a Calabrian cohort: an exploratory genome-wide study.

GeroScience·2026

Same author

Metabolomic signatures of extreme old age: findings from the New England Centenarian Study.

GeroScience·2026

Same author

Identification of novel plasma proteomic biomarkers of Dupuytren disease.

PloS one·2026

Same author

Adherence to various dietary quality indices of centenarian offspring in the New England Centenarian Study.

The journal of nutrition, health & aging·2026

Same author

Factors associated with antimicrobial drug prescription in inpatient dogs and cats at a veterinary teaching hospital.

Journal of veterinary internal medicine·2026

Same journal

Probabilistic RNA designability via interpretable ensemble approximation and dynamic decomposition.

Bioinformatics (Oxford, England)·2026

Same journal

Quantifying domain-specific relevance of computational biology Wikipedia articles using TF-IDF and cosine similarity.

Bioinformatics (Oxford, England)·2026

Same journal

GATSBI: improving context-aware protein embeddings through biologically motivated data splits.

Bioinformatics (Oxford, England)·2026

Same journal

BiMba: using Vision Mamba to predict protein sites that bind other proteins.

Bioinformatics (Oxford, England)·2026

Same journal

ProMeta: a meta-learning framework for robust disease diagnosis and prediction from plasma proteomics.

Bioinformatics (Oxford, England)·2026

Same journal

Is a Win-Win possible? Achieving pareto-optimal privacy-utility balance in fine-tuned genome language model embeddings against embedding reconstruction attacks.

Bioinformatics (Oxford, England)·2026

See all related articles

BMapBuilder creates detailed maps of pairwise linkage disequilibrium (LD) for single nucleotide polymorphisms (SNPs). This tool offers optimized resolution for visualizing LD across entire chromosomes in 2D or 3D.

Area of Science:

Genetics
Bioinformatics
Computational Biology

Background:

Linkage disequilibrium (LD) is crucial for understanding genetic variation and association studies.
Efficient visualization tools are needed for analyzing large-scale genomic data.

Purpose of the Study:

To introduce BMapBuilder, a novel software tool for constructing and visualizing linkage disequilibrium (LD) maps.
To provide a user-friendly platform for exploring LD patterns at the whole-chromosome level.

Main Methods:

BMapBuilder is developed using the Java programming language for cross-platform compatibility.
The software supports the creation of LD maps in both two and three dimensions.

Main Results:

Related Experiment Videos

BMapBuilder generates high-resolution graphical displays of pairwise LD.

The tool facilitates the visualization of LD across entire chromosomes for single nucleotide polymorphisms (SNPs).

Conclusions:

BMapBuilder offers an effective solution for mapping and visualizing pairwise LD.
The optimized resolution enables comprehensive graphical display of LD for SNPs across a whole chromosome.