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Related Experiment Videos

Primary hyperaldosteronism associated with hypertensive emergencies.

Paul T Labinson1, William B White, Beatriz E Tendler

  • 1Section of Hypertension, Pat and Jim Calhoun Center for Cardiology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA.

American Journal of Hypertension
|June 20, 2006
PubMed
Summary

Primary hyperaldosteronism can cause secondary hypertension, often presenting as resistant hypertension or hypertensive crisis. Early diagnosis and treatment, including surgery or medication, lead to good outcomes.

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Area of Science:

  • Endocrinology
  • Nephrology
  • Cardiology

Background:

  • Primary hyperaldosteronism is an increasingly recognized cause of secondary hypertension.
  • It typically presents as hypertension with hypokalemia or resistant hypertension.

Observation:

  • This study reports on eight patients diagnosed with primary hyperaldosteronism who experienced a hypertensive crisis.
  • Elevated serum aldosterone and suppressed plasma renin activity were noted in all patients during the crisis.

Findings:

  • Laparoscopic adrenalectomy was successful in one patient.
  • Seven patients improved with antihypertensive drugs, including an antialdosterone agent.

Implications:

  • Primary hyperaldosteronism should be considered in the differential diagnosis of hypertensive emergencies.

Related Experiment Videos

  • Timely identification and management of primary hyperaldosteronism can prevent severe hypertensive events.