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Updated: Aug 7, 2026

Studying DNA Looping by Single-Molecule FRET
Published on: June 28, 2014
The effect of solvent dynamics on the low frequency collective motions of DNA in solution and unoriented films
K N Woods1, S A Lee, H-Y N Holman
1Ecology Department, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. knwoods2@lbl.gov
Abstract:
Infrared spectroscopy is used to probe the dynamics of in vitro samples of DNA prepared as solutions and as solid unoriented films. The lowest frequency DNA mode identified in the far-infrared spectra of the DNA samples is found to shift in frequency when the solvent influence in the hydration shell is altered. The lowest frequency mode also has characteristics that are similar to beta-relaxations identified in other glass forming polymers.
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