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Published on: July 6, 2016
Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic
Victor K Tam1, Qi Liu, Yitzhak Tor
1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA.
Abstract:
Ethidium bromide has been extended by fusing an additional aromatic ring resulting in a larger intercalator with increased affinity for poly r(A) x r(U), poly d(A) x d(T) and triple helices when compared to the parent heterocycle.

