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Upper gastrointestinal bleeding. With special reference to blood transfusion.
1Department of Surgery, Sundsvall County Hospital, Sweden.
The European Journal of Surgery = Acta Chirurgica
|March 1, 1991
Summary
This study on upper gastrointestinal bleeding found that current treatments lead to low surgery and mortality rates. These findings support the idea that stored blood may counteract a hypercoagulable state in bleeding patients.
Area of Science:
- Gastroenterology
- Internal Medicine
- Hematology
Background:
- Upper gastrointestinal haemorrhage is a significant clinical concern.
- Understanding incidence, diagnosis, treatment, and mortality is crucial for patient outcomes.
Purpose of the Study:
- To review the incidence, diagnosis, treatment, and mortality of upper gastrointestinal haemorrhage.
- To evaluate the effectiveness of current treatment policies.
Main Methods:
- Retrospective review of 978 unselected patients over a 9-year period.
- Analysis of bleeding source, transfusion triggers, surgical interventions, and mortality rates.
Main Results:
- Annual incidence of upper gastrointestinal bleeding was 1/1,000.
- Peptic ulcer was the cause in 53% of admissions.
- Emergency surgery rate was 3%, with a perioperative mortality of 13% and overall mortality of 6%.
Conclusions:
- Current treatment policies for upper gastrointestinal haemorrhage are associated with low rates of operation and mortality.
- Results suggest citrated stored blood may counteract a hypercoagulable state in gastrointestinal bleeding.