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Updated: Aug 7, 2026

An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
Published on: December 25, 2021
[Immunity status in persons with acute radiation disease]
Abstract:
Following the Chernobyl accident those persons having survived acute radiation sickness demonstrated significant decline in the activity of myeloperoxidase in the peripheral blood neutrophilic granulocytes, which fact results in a decrement of bactericidial power of cells. The neutrophilic granulocyte peroxidase activity can hardly ever be referrable to the intensity of oxidative processes in them, which fact is an intriguing issue warranting further study. In analyzing parameters characterizing cell-bound immunity in patients late after the accident persistent changes are recordable in the CD4+ / 8+ ratio. The humoral link of immunity was found to be more labile. We failed to find out established regularities in its abnormalities.
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