Related Experiment Video
Updated: Aug 7, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
[Allergia rhinosinusitis. Diagnosis, programming and treatment monitoring]
Krystyna Obtułowicz1, Jacek Składzień
1Zakład Alergologii Klinicznej i Srodowiskowej, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Abstract:
Allergic rhinitis (AR) is one of the most common airway diseases. About 15% of population suffers from this disease and the prevalence of this illness is still increasing. The symptoms of AR (itching, sneezing, watery nasal discharge) may be persistent or intermittent. Persistent AR often leads to sinusitis (in about 50% of patients), to bronchial asthma (in 40-50% of cases), to conjunctivitis (in > 40%) and to nasal polyps (in 10-15%). The main reasons for AR symptoms are environmental allergens (mites, pollen grains, moulds, animal epithelia) as well as foods, some drugs and chemicals. Diagnosis of AR is based on history, rhinoscopy, cytology of nasal smear. In IgE related AR very important are positive skin prick tests with allergens and the increase of allergen specific IgE in serum. In the treatment of AR most important are: allergen avoidance, topical antihistamins and steroids. Sometimes topical anticholinergics and nasal decongestants are used. In severe symptoms oral antihistamines and oral steroids are needed. In some cases of IgE related AR specific immunotherapy is applied.
Related Concept Videos
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Asthma-IV: Nursing Management
First, in...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Upper Respiratory Drugs: Decongestants
Most decongestants are readily available over-the-counter in various...
