[Oscillator generator in the lower portion of the glycolytic system]

A mathematical model explaining the mechanism of autooscillation generation in the lower part of the glycolytic system is suggested. The model is based on substrate inhibition of glyceraldehydephosphatedehydrigenase (GAPDH) with glyceraldehydephosphate (GAP). Pyrimidinenucleotides (NADplus and NADH) are shown not to play an important role in the given oscillation mechanism and can not be considered to simplify the model.