Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The CAP cancer protocols--a case study of caCORE based data standards implementation to integrate with the Cancer

Jonathan Tobias1, Ram Chilukuri, George A Komatsoulis

  • 1Department of Pathology, University of California at Los Angeles School of Medicine, Los Angeles, CA, USA. jotobias@mednet.ucla.edu

BMC Medical Informatics and Decision Making
|June 22, 2006
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

International Society of Urological Pathology Consensus on Cancer Precursor Lesions: Working Group 3 Preneoplastic and Precursor Lesions of the Kidney.

The American journal of surgical pathology·2026
Same author

CD20-Negative Primary Bone Marrow Large B Cell Lymphoma: A Report of Two Cases with Review of Literature.

South Asian journal of cancer·2025
Same author

Interobserver Reproducibility of Pelvicalyceal Invasion in Renal Cell Carcinoma Nephrectomies Among Genitourinary Pathologists.

The American journal of surgical pathology·2025
Same author

Renal Juxtaglomerular Cell Tumors Exhibit Distinct Genomic and Epigenomic Features and Lack Recurrent Gene Fusions: Comprehensive Molecular Analysis of a Multi-institutional Series.

The American journal of surgical pathology·2024
Same author

Real-World Data on Treatment Outcome of ALK-Positive Non-Small Cell Lung Cancer from an Indian Multicentric Cancer Registry.

South Asian journal of cancer·2024
Same author

Extramedullary haematopoiesis in renal neoplasms.

Histopathology·2024

The Cancer Biomedical Informatics Grid (caBIG) developed a data standard for College of American Pathologists (CAP) cancer protocols. This enables electronic data standards in pathology, improving cancer research informatics.

Area of Science:

  • Bioinformatics
  • Pathology Informatics
  • Cancer Research

Background:

  • The Cancer Biomedical Informatics Grid (caBIG) aims to standardize cancer research data through a multi-tier approach for semantic interoperability.
  • Current pathology reporting standards, like College of American Pathologists (CAP) cancer protocols, lack comprehensive electronic data standards.

Purpose of the Study:

  • To demonstrate the implementation of a caBIG data standard using the CAP cancer protocols and checklists.
  • To illustrate the principles, goals, and methodology for developing caBIG models.

Main Methods:

  • A case study approach was used to implement the Cancer Common Ontologic Representation Environment (caCORE) data standard for the CAP cancer protocols.
  • The process involved developing a model based on existing paper standards and adapting caCORE.

Related Experiment Videos

Main Results:

  • The study details the process, technologies, and data standards used in developing the CAP electronic data model.
  • Difficulties encountered and necessary modifications to caCORE were addressed. Four projects integrating tissue banking and lab systems using CAP data standards are ongoing.

Conclusions:

  • The College of American Pathologists (CAP) cancer checklists can serve as the foundation for an electronic data standard in pathology.
  • The caBIG semantic modeling methodology is suitable for developing these electronic data standards.