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Changes in arterial oxygen tension after gastric lavage for drug overdose
P G Jorens1, E J Joosens, J M Nagler
1Department of Internal Medicine and Intensive Care Medicine, Middelheim General Hospital, Antwerp, Belgium.
Human & Experimental Toxicology
|May 1, 1991
Abstract:
1. Changes in arterial oxygen tension after gastric lavage were investigated in a prospective study of 55 patients admitted for drug overdose. 2. A significantly greater decrease was observed in smokers compared to non-smokers. 3. A correlation was found between the tricyclic antidepressant serum level and the observed oxygen tension decrease. 4. The usefulness, as well as the safety of the lavage procedure, in managing tricyclic antidepressants overdoses is controversial.