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Updated: Aug 7, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Coronary angiography: beyond coronary anatomy]
Armando Pérez de Prado1, Felipe Fernández-Vázquez, J Carlos Cuellas-Ramón
1Sección de Cardiología Intervencionista, Servicio de Cardiología, Hospital de León, Altos de Nava s/n, 24008 León, Spain. aperez@secardiologia.es
Coronary angiography can assess both epicardial and microvascular blood flow after myocardial infarction, offering valuable prognostic information beyond simple blood flow restoration.
Area of Science:
- Cardiology
- Medical Imaging
- Physiology
Background:
- Technical advances allow restoration of epicardial coronary artery blood flow in most myocardial infarction patients.
- Improved myocardial perfusion does not always follow restored blood flow, increasing interest in perfusion assessment.
- Conventional coronary angiography is a widely used technique for evaluating coronary artery blood flow.
Purpose of the Study:
- To evaluate the additional information provided by conventional coronary angiography regarding myocardial perfusion.
- To review data on epicardial and microvascular blood flow assessment using coronary angiography.
- To discuss the prognostic significance of these blood flow parameters.
Main Methods:
- Review of existing data on coronary angiography.
- Analysis of semiquantitative and quantitative assessment of epicardial coronary artery blood flow.
- Evaluation of microvascular blood flow assessment using coronary angiography.
Main Results:
- Coronary angiography provides data on both epicardial and microvascular blood flow.
- Quantitative and semiquantitative assessments of epicardial flow are possible.
- Microvascular function can be inferred from angiographic findings.
Conclusions:
- Conventional coronary angiography offers valuable insights into myocardial perfusion beyond epicardial flow.
- Assessment of both epicardial and microvascular components is crucial for understanding post-myocardial infarction outcomes.
- Angiographic assessment of blood flow has significant prognostic implications.
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