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[Pertussis--not only a childhood disease]

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  • 1Ingo_Stock@web.de

Medizinische Monatsschrift Fur Pharmazeuten
|June 24, 2006
PubMed

Insights

Whooping cough (pertussis), caused by Bordetella pertussis, is a rising respiratory illness. Increased cases in adults and adolescents highlight the need for effective vaccines and macrolide treatments.

Area of Science:

  • Bacteriology
  • Infectious Diseases
  • Immunology

Context:

  • Pertussis (whooping cough) is a highly contagious respiratory infection.
  • Caused by the gram-negative bacterium Bordetella pertussis.
  • Recent years show increased pertussis incidence globally, with a notable shift towards older populations (adolescents and adults).

Purpose:

  • To summarize the current understanding of pertussis epidemiology and management.
  • To highlight the challenges posed by the changing disease patterns.

Summary:

  • Pertussis presents varied symptoms based on age and immunity.
  • Macrolide antibiotics are the primary treatment for Bordetella pertussis infections.
  • Vaccination, particularly with acellular vaccines, remains the most effective preventive measure.

Impact:

  • Understanding the evolving epidemiology of pertussis is crucial for public health strategies.
  • Continued research into vaccine efficacy and treatment options is necessary.
  • Addressing the resurgence in older age groups requires targeted interventions.

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