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St-segment elevation acute myocardial infarction in a patient with acromegaly: a case report and literature review
Ming-Ying Lu1, Pi-Jung Hsiao, Tsung-Hsien Lin
1Department of Internal Medicine, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Insights
This case study highlights acromegaly, a condition of excess growth hormone, presenting as a heart attack. Successful treatment involved coronary angioplasty and managing the pituitary tumor.
Area of Science:
- Endocrinology
- Cardiology
- Oncology
Background:
- Acromegaly, a disorder of excess pituitary growth hormone, leads to characteristic physical changes.
- It significantly increases risks for cardiovascular complications, including cardiomyopathy and coronary artery disease.
Observation:
- A patient with acromegaly presented with ST-segment elevation acute myocardial infarction.
- Typical physical signs of acromegaly prompted further investigation.
Findings:
- Hormonal assays and pituitary imaging confirmed the diagnosis of acromegaly.
- The patient underwent successful primary transluminal coronary angioplasty with stent implantation for the myocardial infarction.
Implications:
- This case underscores the critical link between acromegaly and acute cardiovascular events.
- Early diagnosis and management of acromegaly are vital for preventing severe cardiac complications.
Abstract:
Acromegaly is a disorder caused by the excess production of pituitary growth hormone and is characterized by the enlargement of the hands, feet and head. Increased morbidity and mortality with acromegaly is associated with cardiovascular complications, hypertension, glucose intolerance, cardiomyopathy and coronary artery disease. We report a case of acromegaly, which presented with ST-segment elevation acute myocardial infarction. The patient received successful primary transluminal coronary angioplasty with stent implantation. Acromegaly was suspected from typical appearance, and confirmed with hormonal examination and imaging of the pituitary mass. We discuss this case in comparison with previous literature.
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