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Updated: Aug 7, 2026

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
Published on: December 27, 2017
A number of hematopoietic growth factors and other cytokines are capable of altering platelet production and function. Enhancement of these processes may be exploited to ameliorate bleeding propensity in thrombocytopenic patients. Under certain circumstances, cytokines may have adverse effects on the hemostatic system, potentially involved in thrombogenesis and atherogenesis. Inhibition of those cytokines may prove to be a useful experimental approach to investigate their potential pathophysiologic role.
A number of hematopoietic growth factors and other cytokines are capable of altering platelet production and function. Enhancement of these processes may be exploited to ameliorate bleeding propensity in thrombocytopenic patients. Under certain circumstances, cytokines may have adverse effects on the hemostatic system, potentially involved in thrombogenesis and atherogenesis. Inhibition of those cytokines may prove to be a useful experimental approach to investigate their potential pathophysiologic role.
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